Biography

EDUCATION, DEGREES AND QUALIFICATIONS

  • 1989 - Secondary School – X Belgrade Gymnasium “Mihajlo Pupin”
  • 1995 - Doctor of Medicine, School of Medicine, University of Belgrade.
  • 2000 - Specialist in Pediatrics, School of Medicine, Mother and Child Health Institute, University of Belgrade
  • 2005 - Master of Sciences (Pulmonology), School of Medicine, University of Belgrade, Serbia. Research area: Influence of inhaled corticosteroids on linear growth in children with asthma
  • 2013 - Doctor of Philosophy (Pulmonology), School of Medicine, University of Belgrade, Serbia. Research area: Cardiopulmonary exercise testing in patients with cystic fibrosis
  • 2014 - Assistant Professor of Pediatrics, School of Medicine University of Belgrade, Serbia
  • 2016 - Subspecialist in pediatric pulmonology, School of Medicine University of Belgrade, Serbia. Research area: Respiratory muscle strength in patients with cystic fibrosis

INTERNATIONAL FELLOWSHIPS

  • 2003 - Visiting fellow, Division of Pulmonary and Critical Care Medicine, Department of Pediatrics, Mt. Sinai Hospital, Mt. Sinai School of Medicine, New York, USA. The fields of activities: Pediatric pulmonary medicine, conventional and non-conventional modes of respiratory support.
  • 2003 - Visiting fellow, Division of pediatric pulmonology, Department of Pediatrics, Children’s Hospital, Columbia University, New York, USA. The fields of activities: Respiratory physiology, Pediatric pulmonary medicine.
  • 2005 - Visiting fellow, Service de Pneumologie de l̓enfant et Centre de la mucoviscidose. Hôpital d̓ enfants Armand Trousseau, Paris, France. The fields of activities: Respiratory physiology, non-invasive mechanical ventilation.

POSTQUALIFICATION TRAINING

  • 2003 - “Advanced paediatric respiratory medicine” – ERS School, Barcelona, Spain.
  • 2004 - “Cystic fibrosis – state of the art” – ERS School, Vienna, Austria.
  • 2005 - “Non - invasive positive pressure ventilation – state of the art” – ERS School, Pisa, Italy.
  • 2006 - "Basic principles of clinical exercise testing" – ERS School, Rome, Italy.
  • 2006 - 6th paediatric bronchology course – Imperial College and Royal Brompton hospital, London, UK.
  • 2007 - “Infant pulmonary function testing – state of the art” ERS School, Nice, France.
  • 2007 - “Good Clinical Practice Course” – Association of Clinical Research Professionals, Belgrade, Serbia.
  • 2014 - Scoring Course PG Basic, Poligraphy (Mr. Paul Murphy) – Belgrade, Serbia.
  • 2015 - Scoring Course PG Advanced, Poligraphy (Mr. Paul Murphy) – Belgrade, Serbia.
  • 2016 - The European Workshop on Clinical Pediatric Exercise Testing – Utreht, Netherland

AREA OF RESEARCH

  • Asthma, cystic fibrosis, functional respiratory diagnostics, sleep disordered breathing, pediatric bronchology

MEMBERSHIPS

  • Serbian Pediatric Respiratory Society - president
  • European Respiratory Society
  • American Thoracic Society
  • European Cystic fibrosis Society
  • Association of Clinical Research Professionals
  • Serbian pediatric association
  • The Holy Monastery Hilandar Medical Society

MEMBERSHIP OF THE EDITORIAL BOARD OF SCIENTIFIC PUBLICATIONS

  • 1997 - Problemi u pedijatriji
  • 2015 - Journal of Respiratory Research
  • 2018 - Frontiers in pediatrics

REVIEWER OF SCIENTIFIC PUBLICATIONS

  • European Journal of Pediatrics
  • Frontiers in pediatrics
  • Respiratory Care

PARTICIPATION IN SCIENTIFIC PROJECTS

  • Primary health care of mother and child, supported by UNICEF
  • Rational use of antibiotics in pediatrics, supported by Serbian Ministry of Health

INVITED SPEAKER ON SCIENTIFIC MEETI

  • 2016 - Course of Noninvasive mechanical ventilation, Zagreb, Croatia
  • 2017 - Regional meeting on home mechanical ventilation in pediatrics, Split, Croatia
  • 2018 - Pediatric Noninvasive Ventilation Symposium, Ljubljana, Slovenia
  • 2019 - First Slovenian international symposium on childhood asthma, Bled, Slovenia

INTERNATIONAL MULTICENTER CLINICAL TRIALS

  • Efficacy and safety of ciclesonide in adolescents with asthma. A randomized, double-blind, double dummy, parallel group, multicenter study. ESSENCE BY 9010/M1-139. INVESTIGATOR.
  • Treatment of asthma in pediatric patients. Comparation of inhaled ciclesonide 160 mcg/day and budesonide 400 mcg/day. PeP-Study. BY9010/M1-204. INVESTIGATOR.
  • Safety and tolerability study of SLIT™ Amikacin 500 mg once daily for 14 days by inhalation in cystic fibrosis study subjects chronicaly infected with Pseudomonas aeruginosa. TR02-103. INVESTIGATOR.
  • A Randomized, Double-blind Placebo-controlled, Multicenter, Phase 3 trial to Assess the Efficacy and Safety of Tobramycin Inhalation Powder (TIP) in Cystic Fibrosis (CF) Subjects. TIP002 Study. INVESTIGATOR.
  • Pharmacokinetics of the pharmacologically active metabolite M1 of ciclesonide after inhalation of ciclesonide via MDI with and without AeroChamber Plus spacer in asthmatic children. BY9010/CP-037. INVESTIGATOR
  • Multidose safety nad tolerability study of dose escalation of liposomal amikacin for inhalation (ARIKACE) in cystic fibrosis patients with chronic infection due to Pseudomonas aeruginosa TR02-105. INVESTIGATOR.
  • A Phase III, randomized, double-blind, placebo-controlled clinical study evaluating the efficacy and safety of ALTU-135 treatment in patients with cystic fibrosis-related exocrine pancreatic insufficiency. INVESTIGATOR.
  • A Open-Label clinical study evaluating the long-term safety of ALTU-135 for the treatment of patients with cystic fibrosis-related exocrine pancreatic insufficiency. INVESTIGATOR.
  • Multidose safety nad tolerability study of dose escalation of liposomal amikacin for inhalation (ARIKACE) in cystic fibrosis patients with chronic infection due to Pseudomonas aeruginosa TR02-105 – Extension study. INVESTIGATOR.
  • Randomized open-label, active-controlled, multicenter study to assess the efficacy, safety and tolerability of Arikace in cystic fibrosis patients with chronic infection due to Pseudomonas aeruginosa TR02-108. INVESTIGATOR
  • Long Term Safety and Tolerability of Open-Label Liposomal Amikacin for Inhalation in Cystic Fibrosis Patients With Chronic Infection Due to Pseudomonas Aeruginosa TR02-110. INVESTIGATOR.
  • A Safety and Efficacy Trial of Inhaled Mannitol in Adult Cystic Fibrosis Subjects DPM‐CF‐303. PRINCIPAL INVESTIGATOR
  • Allergic rhinoconjunctivitis study, phase 3, ongoing. INVESTIGATOR
  • A Phase IIa, Randomized, Double-blind, Placebo-controlled Study to Evaluate Multiple Doses of GLPG2222 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del Mutation. INVESTIGATOR
  • „A 2-treatment period, randomized, placebo-controlled, multicenter parallel-group study to assess the safety of QAW039 when added to existing asthma therapy in GINA steps 3, 4 and 5 patients with uncontrolled asthma“
  • А 2-treatment period, randomized, placebo-controlled, multicenter parallel-group study to assess the safety of QAW039 when added to existing asthma therapy in GINA steps 3,4 and 5 patients with uncontrolled asthma.

IMPORTANT REFERENCES IN SCIENTIFIC PUBLICATIONS

  • Cozzi1 G, Sovtic A, Garelli D, Krivec U, Silvagni D, Corsini I, et al. ,SARS-CoV-2 related bronchiolitis. A multicentre international study. Arch Dis Child Arch Dis Child 2023.
  • Basa M, Minic P, Gojsina B, Sovtic A (corresponding author).. Subglottic hemangioma – prevalence, clinical presentation and treatment. Signa Vitae 2023.
  • Baljosevic I, Peric A, Sovtic A. Antic S. Treatment of congenital laryngeal cysts in newborns. Acta Clin Croat 2023; 62:308-12.
  • Perikleous E, Gkentzi D, Bertzouanis A, Paraskakis E, Sovtic A, Fouzas S. Antibiotic Resistance in Patients with Cystic Fibrosis: Past, Present, and future. Antibiotics 2023, 12, 217.
  • Sovtic A. Diagnosis of cystic fibrosis-related diabetes: too early or too late. J Bras Pneumol 2022;48(2):e20220069.
  • Cozzi G, Cortellazzo Wiel L, Amaddeo A, Gatto A, Giangreco M, Klein-Kremer A, Bosis S, Silvagni D, Debbia C, Nanni L, Chiappa S, Minute M, Corsini I, Morabito G, Gortan AJ, Colombo M, Marchetti F, Garelli D, Piffer A, Cardinale F, Levy N, Curatola A, Gojsina B, Basu S, Barbi E, Sovtic A. Prevalence of SARS-CoV-2 positivity in infants with bronchiolitis: a multicentre international study. Arch Dis Child Arch Dis Child 2022; 107:840-844.
  • Stevanovic N, Skakic A, Minic P, Sovtic A, Stojiljkovic M, Pavlovic S, Andjelkovic M. Identification and classification of novel genetic variants: en route to the diagnosis of primary ciliary dyskinesia. Int J Mol Sci 2021, 22, 8821.
  • Gojsina B, Minic P, Todorovic S, Soldatovic I, Sovtic A (corresponding author). Continous glucose monitoring as a valuable tool in the early detection of diabetes related to cystic fibrosis. Front Ped 2021; 9: 659728.
  • Sovtic A, Grba T, Grahovac D, Minic P. Flexible Bronchoscopy in Evaluation of Persistent Wheezing in Children — Experiences from National Pediatric Center. Medicina 2020; 56: 329.
  • Markovic-Sovtic G, Djuricic S, Sovtic A, Minic P, Rakonjac Z, Colmero I. Neonatal generalized lymphatic anomaly (GLA) with skin involvement. Ann Dermatol 2020 (M23 IF 1,647).
  • Sovtic A, Grba T, Grahovac D, Minic P. Flexible Bronchoscopy in Evaluation of Persistent Wheezing in Children — Experiences from National Pediatric Center. Medicina 2020; 56: 329 (M22, IF 1,467).
  • Basa M, Minic P, Rodic M, Sovtic A. (corresponding author). Evolution of pediatric home mechanical ventilation program in serbia – what has changed in the last decade. Front Ped 2020; 8:261. M21, IF 2,349.
  • Plavsic L, Knezevic M, Sovtic A, Minic P, Vukovic R, Mazibrada I, Stanojlovic O, Hrncic D, Rasic-Markovic A, Macut D.Effects of high-intensity interval training and nutrition advice on cardiometabolic markers and aerobic fitness in adolescent girls with obesity. Appl Physiol Nutr Metab. 2020; 45: 294-300. M21 IF 3,455
  • Paglietti M, Porcaro F, Sovtic A, Cherchi C, Verrillo E, Pavone M, Bottero S, Cutrera R. Decanulation in children affected by congenital central hypoventilation syndrome: A proposal of an algorithm from two European centers. Pediatr Pulmonol 2019; 54: 1663-9. M21 IF 2,534
  • Marković-Sovtić G, Nikolić T, Sovtic A, Martic J, Rakonjac Z. Pulmonary air leak syndrome in term and late preterm neonates. Srp Arh Celok Lek 2019. Online First July 18, 2019. M 23 IF 0,299
  • Andjelković M, Spasovski V, Vreća M, Sovtić A, Rodić M, Komazec J, Pavlović S, Minić P. The importance of genomic profiling for differential diagnosis of pediatric lung disease patients with suspected ciliopathies. Srp Arh Celok Lek 2019│Online First March 4, 2019. M23 IF 0,299
  • Andjelkovic M, Minic P, Vreca M, Stojiljkovic M, Skakic A, Sovtic A, Rodic M, Skodric-Trifunovic V, Maric N, Visekruna J, Spasovski V, Pavlovic S. Genomic profiling supports the diagnosis of primary ciliary dyskinesia and reveals novel candidate genes and genetic variants. PLoS One. 2018 Oct 9;13(10):e0205422. M21; IF 2,766.
  • Sovtic A, Minic P, Markovic-Sovtic G, Trajkovic G. Respiratory muscle strength and exercise a. performance in cystic fibrosis–A cross sectional study. Front Pediatr 2018; 6:244. M21; IF:2,335.
  • Gojsina B, Rodic M, Visekruna J, Trajkovic G, Sovtic A (corresponding author), Minic P. Pulmonary exacerbations as a risk factor for lung function decline- experiences of national cystic fibrosis center. Vojnosanit Pregl (2018); Online First January, 2018. M23 IF 0,272
  • Radtke T, Hebestreit H, Gallati S, Schneiderman JE, Braun J, Stevens D, Hulzebos EH, Takken T, Boas SR, Urquhart DS, Lands LC, Tejero S, Sovtic A, et al. CFTR Genotype and Maximal Exercise Capacity in Cystic Fibrosis: A Cross-sectional Study. Ann Am Thorac Soc 2018;15(2):209-216. M21 IF 4,006.
  • Malešević M, Vasiljević Z, Sovtić A, Filipić B, Novović K, Kojić M, Jovčić B. Virulence traits associated with Burkholderia cenocepacia ST856 epidemic strain isolated from cystic fibrosis patients. Antimicrob Resist Infect Control. 2017 Jun 6;6:5. M22; IF 2,716
  • Minic P, Sovtic A. Exercise intolerance and exercise-induced bronchoconstriction in children. Front Biosci 2017; 9:21-32. M22; IF 2,484
  • Vasiljevic Z, Novovic K, Kojic M, Minic P, Sovtic A, Djukic S, Jovcic B. Burkholderia cepacia complex in Serbian patients with cystic fibrosis: prevalence and molecular epidemiology. Eur J Clin Microbiol Infect Dis 2016; 35:1277-84. M22; IF 2,857
  • Marković D, Perić T, Sovtić A, Minić P, Mirković B. Stanje oralnog zdravlja kod dece obolele od astme. Srp Arh Celok Lek 2015;143:539-44. M23; IF 0,277
  • Baljosevic I, Minic P, Trajkovic G, Markovic-Sovtic G, Radojicic B, Sovtic A (corresponding author). Evaluation of surgical treatment of severe laryngomalacia - follow up study. Pediatr Int 2015; 57:1159-63. M23; IF 0,952
  • Sovtic A, Minic P, Kosutic J, Markovic-Sovtic G, Gajic M. Modified Chrispin-Norman score: correlation with peak exercise capacity and efficiency of ventilation in children with cystic fibrosis. Pediatr Exerc Sci 2014; 26:259-65. M22, IF 2,085.
  • Markovic-Sovtic G, Kosutic J, Jankovic B, Bojanin D, Sovtic A, Radojicic Z, et al. NT-pro BNP In Assessment Of Respiratory Distress In Term Neonates. Pediatr Int 2014; 56:373-7. M23; IF 0,865
  • Sovtic A, Minic P, Kosutic J, Markovic-Sovtic G, Gajic M. Static hyperinflation is associated with decreased exercise performance in children with cystic fibrosis. Respir Care 2013; 58:291–7. M22; IF 2,037
  • Radivojevic D, Sovtic A, Minic P, Grkovic S, Guc-Scekic M, Lalic T, et al. Newborn screening for cystic fibrosis in Serbia - a pilot study. Pediatr Int 2013; 55:181-4. M23; IF 0,810.
  • Sovtic A, Minic P, Vukcevic M, Markovic-Sovtic G, Rodic M, Gajic M. Home mechanical ventilation in children is feasible in developing countries. Pediatr Int 2012; 54:676-81. M23; IF 0,921.
  • Kosutic J, Minic P, Sovtic A, Prijic S. Upper lung lobe systemic artery-pulmonary vein fistula with signs and symptoms of congestive heart failure: successful treatment with coil embolization. J Vasc Interv Radiol 2007; 18:299-302. M21; IF 2,571.
  • Sovtić A, Minić P, Bogdanović R, Stajić N, Rodić M, Marković-Sovtić G. Atypical presentation of cystic fibrosis – obese adolescent with hypertension and Pseudo-Bartter’s syndrome. Vojnosanit Pregl 2012; 64:367-9. M23; IF 0,210.
  • Savić N, Janković B, Minić P, Vasiljević Z, Sovtić A, Pejić K et al. Clinical characteristics of respiratory syncytial virus infection in neonates and young infants. Vojnosanit Pregl 2011; 68:220-4. M23; IF 0,179.

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